CT findings of ovarian sertoli-leydig cell tumor

VernacularTitle:卵巢支持-间质细胞瘤的CT表现
Author: Heng LIU ; Zetian DONG ; Yonghua BO ; Kexin HUANG ; Bangguo LI ; Tijiang ZHANG
Keywords: ovarian; sertoli-leydig cell tumor; computed tomography; pathology
From: Journal of Practical Radiology 2017;33(7):1059-1061
CountryChina
Language:Chinese
Abstract: Objective To study the CT findings of ovarian sertoli-leydig cell tumor (SLCT),to improve the understanding of SLCT imaging features.Methods CT images of 6 cases were reviewed retrospectively.CT plain scan was performed in 6 patients;CT enhancement scan was performed in 4 patients.Results All tumors were unilateral.On non-enhanced CT,5 cases showed cystic-solid masses with clear margin,and 1 case showed solid mass.After contrast administration,the cystic walls,septum and solid portions showed progressively obvious enhancement.Of these 6 cases, 3 cases showed increased testosterone levels,2 cases had high prolactin level,and 1 case was with raised AFP in plasma.Positive expressions of immunohistochemical markers were as following:Inhibin-α (6 cases),Vimentin (4 cases),Calretinin (2 cases), CD99 (1 case), Ki-67 (1 case), CK20 (1 case).Conclusion CT findings of SLCT have some certain characteristics, especially a unilateral, cystic-solid and well-defined mass, and marked solid part enhancement on contrast CT.Combined with clinical findings, especially increased plasma testosterone levels, SLCT should be included in the differential diagnosis of regional tumors.