The Effects of Aging on the Brain Stem Speech Encoding in Spontaneous Post-menopause Women
	    		
		   		
		   			
		   		
	    	
    	 
    	10.3969/j.issn.1006-7299.2017.03.005
   		
        
        	
        		- VernacularTitle:年龄对自然更年期后女性脑干言语编码能力的影响
 
        	
        	
        	
        		- Author:
	        		
		        		
		        		
			        		Yi ZHANG
			        		
			        		;
		        		
		        		
		        		
			        		Chunyan WANG
			        		
			        		;
		        		
		        		
		        		
			        		Jinfeng LIU
			        		
			        		;
		        		
		        		
		        		
			        		Xiaoting LI
			        		
			        		;
		        		
		        		
		        		
			        		Xin FU
			        		
			        		;
		        		
		        		
		        		
			        		Ningyu WANG
			        		
			        		
		        		
		        		
		        		
		        		
		        		
			        		
			        		
		        		
	        		
        		 
        	
        	
        	
        	
        		- Keywords:
        			
	        			
	        				
	        				
			        		
				        		Speech;
			        		
			        		
			        		
				        		Auditory brainstem responses;
			        		
			        		
			        		
				        		Bilateral ovariectomized women;
			        		
			        		
			        		
				        		Post-menopause women
			        		
			        		
	        			
        			
        		
 
        	
            
            
            	- From:
	            		
	            			Journal of Audiology and Speech Pathology
	            		
	            		 2017;25(3):238-241
	            	
            	
 
            
            
            	- CountryChina
 
            
            
            	- Language:Chinese
 
            
            
            	- 
		        	Abstract:
			       	
			       		
				        
				        	Objective To investigate the effects of aging on the brain stem speech encoding in spontaneous post-menopause women.Methods There were twenty post-menopause women with normal hearing for test and twenty ovariectomized women with normal hearing for contrast.Speech-evoked auditory brainstem response (speech-ABR) was used.The speech syllable /da/ as stimulus sound was transmitted to right ear by the insert earphones in speech-ABR test.Results Response waves of speech-ABR in ovariectomized women were similar to those in post-menopause women, which contained the onset response (peak V and A), the transition (peak C), the frequency following responses (peak D, E and F) and the offset response (peak O).The characteristics of speech-ABR's peak latency and magnitude were similar between the two groups.Except that the bilateral ovariectomized women had a shorter latency of waves O for the transient response (P<0.01), the larger amplitude of peak F for the periodic portion than post-menopause women (P<0.05).No significant differences were found in the amplitude the latency of the other waves, and V/A slope between bilateral ovariectomized women (0.21±0.10 μV /ms)and post-menopause women (-0.20±0.09 μV/ms) was similar and had no statistical significance (P>0.05).After the combination of ovariectomized women and post-menopause women, the age of these subjects was positively correlated with the latency of O wave (P<0.05).Others had no correlation with age in the amplitude and latency of the waves of speech-ABR.Conclusion Aging does not affect on brain stem speech encoding in spontaneous post-menopause women.