A retrospective study of the treatment for epithelial-myoepithelial carcinoma
10.3760/cma.j.issn.1004-4221.2017.05.006
- VernacularTitle:上皮-肌上皮癌的临床特点与疗效分析
- Author:
Jianghu ZHANG
;
Xiaodong HUANG
;
Li GAO
;
Junlin YI
;
Lin YANG
;
Peiqing MA
;
Guozhen XU
;
Jingwei LUO
;
Jiangping XIAO
;
Kai WANG
;
Yuan QU
;
Shiping ZHANG
- Keywords:
Head and neck neoplasms/surgery;
Head and neck neoplasms/radiotherapy;
Epithelial myoepithelial carcinoma
- From:
Chinese Journal of Radiation Oncology
2017;26(5):513-516
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the risk of locoregional recurrence (LRR) and the influencing factors for long-term survival in patients with epithelial-myoepithelial carcinoma (EMCa).Methods A retrospective analysis was performed for 18 EMCa patients, who received initial therapy or initial adjuvant therapy in our hospital from 1999 to 2015, to investigate their survival.Among these patients, 8(44%) underwent surgery alone, 9(50%) received adjuvant radiotherapy, and 1(6%) received radical concurrent chemoradiotherapy.Locoregional recurrence-free survival (LRFS) and overall survival (OS) rates were compared between these groups.The Kaplan-Meier mtthod was used to calculated survival rates and log-rank test was used to compare the LRFS.Results With a median follow-up time of 46 months, 5 patients developed LRR, and the 5-year LRFS and OS rates were 69% and 93%, respectively.The patients treated with radiotherapy had a significantly higher 5-year LRRFS rate than those not treated with radiotherapy (71% vs.57%, P=0.569).Conclusions LRR is the main failure mode of EMCa treatment, and further improving local control is the key to improved survival.
