Efficacy of alendronate sodium combined with dietary and exercise intervention in postmenopausal osteoporosis
10.3969/j.issn.1005-1678.2017.01.047
- VernacularTitle:阿仑膦酸钠联合营养运动干预用于绝经后骨质疏松症的疗效
- Author:
Jing GAO
;
Chunying MAO
;
Jianxia ZHANG
;
Hui JIN
;
Yujin FENG
;
Xiaojun RAO
- Keywords:
osteoporosis;
postmenopause;
alendronate sodium;
dietary and exercise intervention
- From:
Chinese Journal of Biochemical Pharmaceutics
2017;37(1):163-164,168
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the efficacy of alendronate sodium combined with dietary and exercise intervention in postmenopausal osteoporosis. Methods 88 postmenopausal osteoporosis patients were enrolled and treated with alendronate sodium and Vitamin D combined with dietary and exercise intervention for 12 months. Bone mineral density (BMD) of lumber spine and femur neck were measured before and after the treatment. Results Medication combined with dietary and exercise intervention significantly increased bone mineral density of postmenopausal osteoporosis patients, and the serum levels of bone alkaline phosphatase (BLAP), alkaline phosphatase (AKP) and tartrate resistant acid phosphatase (TRACP) were significantly higher than those pre-treatment, with significant differences (P<0.05). Conclusion Compared to simple medication treatment, medication combined with dietary and exercise intervention is more effective to enhance medication efficacy and BMD level.
