Cell-free fetal nucleic acid in maternal plasma and noninvasive prenatal paternity testing
10.13618/j.issn.1001-5728.2016.06.014
- VernacularTitle:母血浆中胎儿游离核酸与无创性产前亲子鉴定
- Author:
Jin YU
;
Chao XIAO
;
Daixin HUANG
- Keywords:
forensic biological evidence;
noninvasive prenatal paternity testing;
cell-free fetal nucleic acid;
differentially methylated region
- From:
Chinese Journal of Forensic Medicine
2016;31(6):587-590,594
- CountryChina
- Language:Chinese
-
Abstract:
In recent years, the cases of prenatal paternity testing gradually increased in forensic practice. The traditional prenatal paternity analysis can be performed only after invasive sampling of chorionic villi or amniotic fluid, which can result in a risk of miscarriage. The existence of circulating cell-free fetal nucleic acid in maternal plasma has brought new opportunities for the noninvasive prenatal paternity testing. In this paper, the research situation and application prospect of circulating cell-free fetal nucleic acid in maternal plasma in prenatal paternity testing are reviewed.
