To investigate the relationship of antithrombin-Ⅲ activity and thrombosis risk in liver cirrhosis with child-pugh classification

VernacularTitle:抗凝血酶Ⅲ活性检测对肝硬化分级患者血栓风险评估的价值
Author: Bin GUO ; Ning XIE ; Meng YU ; Xiao CHEN ; Xueqin ZHAN ; Zhonghai FEI ; Junan LI
Publication Type:Journal Article
Keywords: antithrombin-Ⅲ; hepatitis B cirrhosis; child-pugh; D-dimer
From: International Journal of Laboratory Medicine 2016;37(18):2581-2582,2586
CountryChina
Language:Chinese
Abstract: Objective To investigate the relationship of antithrombin‐Ⅲ activity and thrombosis risk in liver cirrhosis with Child‐Pugh classification .Methods In our hospital from June to December 2014 ,60 liver cirrhosis patients were selected randomly included into this experiment group ,The 60 cases of control group were from medical examination of health in our hospital .The plasma AT‐Ⅲ activity and D‐D concentration in all these cases were detected and analyzed .Results The AT‐Ⅲ in cirrhosis patients were significantly lower than which in healthy persons(P<0 .05) .The lower level of AT‐Ⅲ is in these patients which were in seri‐ous condition(P<0 .05) ,the abnormal rate of D‐D concentration is also higher at the same time(P<0 .05) .Conclusion The detec‐tion of AT‐Ⅲ level in patients with liver cirrhosis is directly related to the severity of clinical and thrombosis risk .The AT‐Ⅲ de‐tection level can be used to judge the patient′s condition and develop appropriate treatment strategies .