The research progress of quassinoids components in Brucea javanica and their pharmacological activities
	    		
		   		
		   			
		   		
	    	
    	 
    	10.3969/j.issn.1001-1978.2016.11.001
   		
        
        	
        		- VernacularTitle:鸦胆子苦木内酯类成分及其药理活性研究进展
 
        	
        	
        	
        		- Author:
	        		
		        		
		        		
			        		Lixia FU
			        		
			        		;
		        		
		        		
		        		
			        		Chonggang HUANG
			        		
			        		;
		        		
		        		
		        		
			        		Mingbao LIN
			        		
			        		;
		        		
		        		
		        		
			        		Qi HOU
			        		
			        		
		        		
		        		
		        		
		        		
		        		
			        		
			        		
		        		
	        		
        		 
        	
        	
        	
        		- Publication Type:Journal Article
 
        	
        	
        		- Keywords:
        			
	        			
	        				
	        				
			        		
				        		Brucea javanica L. Merr;
			        		
			        		
			        		
				        		quassinoids;
			        		
			        		
			        		
				        		pharmacolog-ical activities;
			        		
			        		
			        		
				        		anti-tumor;
			        		
			        		
			        		
				        		anti-inflammation;
			        		
			        		
			        		
				        		research progress
			        		
			        		
	        			
        			
        		
 
        	
            
            
            	- From:
	            		
	            			Chinese Pharmacological Bulletin
	            		
	            		 2016;32(11):1481-1485,1486
	            	
            	
 
            
            
            	- CountryChina
 
            
            
            	- Language:Chinese
 
            
            
            	- 
		        	Abstract:
			       	
			       		
				        
				        	Fructus Bruceae, the dry and ripe fruits of Brucea ja-vanica( L. ) Merr. ( Simaroubaceae) , has been used for dysenter-y, tumor, malaria and furunculosis treatment, and topical appli-cation for warts and corns. Quassinoids are the main chemical constituents of Fructus Bruceae, which have been proved to have anti-tumor, anti-inflammatory, insecticidal, anti-viral, anti-bac-terial and hypoglycemic activities, and so on. In view of the ex-tensive pharmacological activities of Fructus Bruceae, and better development and utilization of its medicinal value, the advances of quassinoids in Fructus Bruceae and their pharmacological ac-tivities are reviewed in this paper.