Molecular mechanism of acute kidney injury and intervention by Chinese medicine
10.3969/j.issn.1001-1978.2016.11.004
- VernacularTitle:急性肾损伤的分子机制及中药干预研究进展
- Author:
Lianhong YIN
;
Meng QI
;
Jinyong PENG
- Publication Type:Journal Article
- Keywords:
acute kidney injury;
ischemia/reperfusion;
patho-genesis;
traditional Chinese medicine;
natural product;
preven-tion and treatment
- From:
Chinese Pharmacological Bulletin
2016;32(11):1494-1499,1500
- CountryChina
- Language:Chinese
-
Abstract:
Acute kidney injury (AKI), a common clinical dis-ease, is one complex pathophysiological process. In this review paper, the relationship and the molecular mechanisms of ische-mia-reperfusion, major surgery, rhabdomyolysis, pus sepsis and drug-induced renal toxicity associated with AKI were comprehen-sively reviewed. In addition, the prevention and treatment of AKI by Chinese medicine and the effective components were also reviewed. Therefore, our review aims to provide valuable infor-mation for treatment of AKI, and also for exploration of innova-tive new drugs.
