Progress study of miRNA in papillary thyroid carcinoma
10.3760/cma.j.issn.1674-6090.2016.01.018
- VernacularTitle:miRNA在甲状腺乳头状癌中的研究新进展
- Author:
Jinwang DING
;
Keyi WANG
;
Chen LI
;
Jingjing SHI
;
Liuqing YE
;
Dingcun LUO
- Publication Type:Journal Article
- Keywords:
MiRNA;
Papillary thyroid carcinoma
- From:
Chinese Journal of Endocrine Surgery
2016;10(1):71-73,77
- CountryChina
- Language:Chinese
-
Abstract:
MiRNAs represent a class of short endogenous non-coding RNAs regulating gene expression at mRNA post-transcriptional level in many biological processes,including differentiation,proliferation,development and apoptosis.The deregulation of miRNA expression is believed to be an important regulator of tumor development.Increasing evidence has revealed the abnormal expression of miRNA in papillary thyroid carcinoma,indicating the important role in PTC invasion mechanism,clinical diagnostic value,efficacy evaluation,recurrence monitoring and prognosis judgement.
