Rapidly resolved IgG4-related retroperitoneal fibrosis after steroid pulse therapy.
10.12701/yujm.2016.33.1.40
- Author:
Soomin JEUNG
1
;
Hyosang KIM
;
Yuri SEO
;
Hee Young YOON
;
Nah Kyum LEE
;
Shinhee PARK
;
Bomi SEO
;
Su Yeon PARK
;
Su Kil PARK
Author Information
1. Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea. skpark@amc.seoul.kr
- Publication Type:Case Report
- Keywords:
Glucocorticoids;
IgG4-related disease;
Retroperitoneal fibrosis;
Steroid pulse therapy
- MeSH:
Glucocorticoids;
Humans;
Immunoglobulins;
Inflammation;
Methylprednisolone;
Middle Aged;
Prednisone;
Retroperitoneal Fibrosis*
- From:Yeungnam University Journal of Medicine
2016;33(1):40-43
- CountryRepublic of Korea
- Language:English
-
Abstract:
Retroperitoneal fibrosis (RF) is a disorder characterized by the presence of a retroperitoneal mass and concurrent systemic inflammation. Some cases of RF are recognized as belonging to the spectrum of immunoglobulin G4-related disease (IgG4-RD). Glucocorticoids are highly effective for treatment of retroperitoneal fibrosis, although the optimal dose and duration of therapy have not been established. An initial dose of prednisone (40-60 mg) daily is usually administered with a tapering scheme. We report on a 55-year-old man diagnosed with IgG4-related RF and successfully treated with a 3-day course of daily 250 mg (4 mg/kg) intravenous methylprednisolone, which resulted in the prompt resolution of urinary obstruction and systemic symptoms.
