Research progress on the cellular uptake mechanism of nanoparticles
10.3760/cma.j.issn.1673-4181.2015.01.014
- VernacularTitle:纳米粒摄取机制的研究进展
- Author:
Chao ZHANG
;
Guilei MA
- Publication Type:Journal Article
- Keywords:
Nanoparticles;
Uptake mechanism;
Influencing factors
- From:
International Journal of Biomedical Engineering
2015;38(1):57-62,后插7
- CountryChina
- Language:Chinese
-
Abstract:
With the development of nanotechnology,nanomaterials have great application potential in drug delivery system.Understanding the cellular uptake mechanism of nanoparticles has important scientific significance and application value in understanding life processes in cellular level,mechanisms of drug action and gene therapy,which provides the basis for developing safer and more effective nanosized drug carrier.This review summarizes the latest advancement about cellular uptake mechanisms of nanopatricles.Based on a brief introduction of the endocytic pathway of nanoparticles,influencing factors of endocytosis pathway are discussed,and the common methods used to study nanoparticle endocytosis pathways are also introduced in detail.
