The relationship between concentration of oxidized low density lipoprotein and carotid intima-media thickness in patients with acute cerebral infarction
10.3969/j.issn.1673-4130.2015.03.006
- VernacularTitle:急性脑梗死患者氧化低密度脂蛋白与颈动脉内膜中层厚度的关系探讨
- Author:
Xiaohong WU
;
Xiongwen SHEN
;
Xiaoyan YE
;
Qutong CHEN
- Publication Type:Journal Article
- Keywords:
acute cerebral infarction;
oxidized low density lipoprotein;
intima-media thickness
- From:
International Journal of Laboratory Medicine
2015;(3):301-302,305
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the relationship between the concentration of oxidized low density lipoprotein(Ox-LDL)and ca-rotid intima-media thickness(IMT)in acute cerebral infarction(ACI group).Methods 44 ACI patients(ACI group)and 30 healthy individuals(control group)were enrolled in the study,whose serum concentrations of Ox-LDL were determined by using enzyme-linked immunosorbent assay(ELISA),and carotid IMT of ACI patients were measured by using ultrasound,then the relationship between Ox-LDL and carotid IMT of ACI patients was analysed.Results The serum concentration of Ox-LDL in ACI group was significantly higher than that in control group(P <0.01).In ACI group,the serum concentration of Ox-LDL was positively correla-ted with carotid IMT(r =0.493,P <0.05 ).In ACI group,the serum Ox-LDL concentrations of patients whose IMT≥1.0 were higher than patients whose IMT<1.0 mm(P <0.05).Ox-LDL concentrations of ACI patients were positively correlated with the carotid IMT(r =0.493,P <0.05 ).Conclusion The serum concentration of Ox-LDL increased significantly in ACI patients,and was closely related to carotid atherosclerosis.
