Value of procalcitonin and high sensitivity C-reactive protein in early diagnosis of neonatal septicemia
10.3969/j.issn.1673-4130.2014.20.014
- VernacularTitle:降钙素原和超敏C反应蛋白联合检测在新生儿败血症早期诊断的价值研究
- Author:
Baosheng DUAN
;
Na ZHAO
;
Chao LIANG
;
Yanhai WANG
- Publication Type:Journal Article
- Keywords:
procalcitonin;
high sensitivity C-reactive protein;
neonatal septicemia;
disease assessment
- From:
International Journal of Laboratory Medicine
2014;(20):2754-2755,2757
- CountryChina
- Language:Chinese
-
Abstract:
Objective Too investigate the application value of procalcitonin(PCT)and high sensitivity C-reactive protein(hs-CRP)in early diagnosis of neonatal septicemia and disease condition assessment.Methods 48 patients with neonatal septicemia treated in the hospital from November 2011 to May 2013 were collected.The data of PCT,hs-CRP and blood culture were recorded and performed the comparative analysis with the serum PCT,hs-CRP detection results in contemporaneous 48 neonates without septicemia.Results The serum PCT and hs-CRP was 93.75% and 10.42% in the neonates with septicemia,which were signifi-cantly higher than 79.17% and 50% in the neonates without septicemia(P <0.05),the positive rate had statistical difference be-tween the two groups.Conclusion PCT and hs-CRP have remarkable change in the early stage of neonatal sepsis,the combination detection of serum PCT and hs-CRP can be used as the indicators for early diagnosis of neonatal sepsis,moreover the sensitivity and specificity of PCT for diagnosing neonatal septicemia are higher the those of hs-CRP,their combined detection can provide fast and accurate diagnostic basis for clinic.
