The preliminary research of DWIBS in lymph node metastasis of rectal cancer
	    		
		   		
		   			
		   		
	    	
    	 
    	10.3969/j.issn.1002-1671.2014.11.016
   		
        
        	
        		- VernacularTitle:DWIBS 对直肠癌淋巴结转移的初步研究
 
        	
        	
        	
        		- Author:
	        		
		        		
		        		
			        		Xuehuan LIU
			        		
			        		;
		        		
		        		
		        		
			        		Jun LIU
			        		
			        		;
		        		
		        		
		        		
			        		Jin ZHONG
			        		
			        		;
		        		
		        		
		        		
			        		Liang XU
			        		
			        		;
		        		
		        		
		        		
			        		Xiuling ZHANG
			        		
			        		;
		        		
		        		
		        		
			        		Caixian HAO
			        		
			        		;
		        		
		        		
		        		
			        		Changqing ZONG
			        		
			        		;
		        		
		        		
		        		
			        		Hui QIAO
			        		
			        		
		        		
		        		
		        		
		        		
		        		
			        		
			        		
		        		
	        		
        		 
        	
        	
        	
        		- Publication Type:Journal Article
 
        	
        	
        		- Keywords:
        			
	        			
	        				
	        				
			        		
				        		diffusion-weighted imaging with background suppression;
			        		
			        		
			        		
				        		apparent diffusion coefficient;
			        		
			        		
			        		
				        		rectal cancer;
			        		
			        		
			        		
				        		lymph node
			        		
			        		
	        			
        			
        		
 
        	
            
            
            	- From:
	            		
	            			Journal of Practical Radiology
	            		
	            		 2014;(11):1839-1841,1854
	            	
            	
 
            
            
            	- CountryChina
 
            
            
            	- Language:Chinese
 
            
            
            	- 
		        	Abstract:
			       	
			       		
				        
				        	Objective To investigate the application value of diffusion-weighted imaging with background suppression (DWIBS) in lymph node metastasis of rectal cancer.Methods 30 patients with rectal cancer diagnosed by colonoscopy underwent routine MRI and DWIBS examinations.Metastatic and non-metastatic lymph nodes were confirmed by postoperative pathology.Apparent diffu-sion coefficient (ADC)values of the solid part of metastatic and non-metastatic lymph nodes were measured and compared.ROC curve analysis was used to define the threshold between the metastatic and non-metastatic lymph nodes.Results In all 73 lymph nodes,there were 52 metastatic lymph nodes and the other 21 were non-metastatic.ADC values of the solid part of metastatic and non-metastatic lymph nodes were (0.881 ± 0.094)× 10 -3 mm2/s and (1.072 ± 0.108)×10 -3 mm2/s respectively,the difference was statistically significant (P <0.05).With the threshold ADC value of 0.957×10 -3 mm2/s,the sensitivity and specificity for dif-ferentiating metastatic from non-metastatic lymph nodes were 90.5% and 80.8% respectively.The diagnostic value was excellent (Az value = 0.91 9,P <0.05).Conclusion ADC values may be used to differentiate lymph node metastasis of rectal cancer,and DWIBS has higher application value in assessing lymph node metastasis of rectal cancer.