Relationship among ambulatory pulse pressure, pulse pressure index and carotid intima-media thickness in aged patients with hypertension
10.3969/j.issn.1008-0074.2011.06.
- VernacularTitle:老年高血压患者动态脉压和脉压指数与颈动脉内膜-中层厚度的关系
- Author:
Jin XU
;
Penghong LI
;
Jia CHEN
;
Xin WU
- Publication Type:Journal Article
- Keywords:
Hypertension;
Blood pressure monitoring, Ambulatory;
Carotid arteries;
Arteriosclerosis
- From:
Chinese Journal of cardiovascular Rehabilitation Medicine
2011;20(6):504-508
- CountryChina
- Language:English
-
Abstract:
Objective: To study relationship among ambulatory pulse pressure (PP), pulse pressure index (PPI) and carotid intima-media thickness (IMT) in aged patients with hypertension. Methods: The 24h ambulatory blood pressures of 159 subjects were measured, and their ambulatory PP [(mean systolic blood pressure (SBP) - mean diastolic blood pressure (DBP)] and ambulatory PPI (ambulatory PP/mean SBP) were calculated. Color Doppler ultrasonography was used to measure carotid IMT. Relationship between ambulatory PPI and carotid IMT was analyzed. Results: Pearson correlation analysis indicated that carotid IMT was correlated with age (r=0.353), mean SBP (r=0.594), mean DBP (r=-0.355), ambulatory PP (r=0.855) and ambulatory PPI (r=0.883), P<0.001 all. Multivariant gradual regressive analysis indicated that carotid IMT possessed significant linear correlation with ambulatory PP and ambulatory PPI (R2=0.789), and standardized regression coefficient β of ambulatory PPI (β=0.621) was higher than that of ambulatory PP (β=0.284). Conclusion: Ambulatory pulse pressure index and ambulatory pulse pressure are good indicators for evaluation of carotid arteriosclerosis, and value of ambulatory pulse pressure index is more than.
- Full text:P020120114769284219495.doc
