Study on cobra venom factor
- VernacularTitle:眼镜蛇毒抗补体因子的研究
- Author:
Chunling YE
;
Xianda REN
;
Yanqing LU
;
Kaihe YE
- Publication Type:Journal Article
- From:
Chinese Journal of Pathophysiology
2001;17(5):473-476,480
- CountryChina
- Language:Chinese
-
Abstract:
Cobra venom factor (CVF), separated from the cobra venoms, is an acidic glucoproteins with anticomplementory activity. The combination of CVF with factor B in the blood produces a stable C3 and C5 converterase resulting in complement depletion by activating complement continually. There are many studies on it, such as inflammation, autoimmune disease, xenotransplantation, anti-tumor, etc. CVF is also an important tool drug for the study of complement role in the pathophysiological development of diseases.
