Clinical Efficacy of Cefoperazone/sulbactam for Acute Exacerbation of Chronic Obstructive Pulmonary Disease
- VernacularTitle:头孢哌酮/舒巴坦治疗重度慢性阻塞性肺疾病急性加重期临床分析
- Author:
Hongying MA
;
Bin WAN
;
Zaichun DENG
;
Lei CHEN
;
Baohong CHEN
- Publication Type:Journal Article
- Keywords:
Severe chronic obstructive pulmonary disease;
Acute exacerbation;
Cefoperazone/sulbactam
- From:
Chinese Journal of Nosocomiology
2009;0(24):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE To evaluate the clinical efficacy of cefoperazone/sulbactam(Sulperazon) for acute exacerbation of chronic obstructive pulmonary disease(AECOPD).METHODS A total of 136 cases of AECOPD were randomized into cefoperazone/sulbactam group and ceftazidime group,and sputum culture of each case was underwent before and after treatment.RESULTS The total efficacy rates and bacterial clearance rates in cefoperazone/sulbactam group and ceftazidime group were 91.18%,96.67% and 70.59%,75.86%,respectively,and the differences between the two groups were statistically significant.CONCLUSIONS It suggested that cefoperazone/sulbactam be a more effective drug for AECOPD.
