Clinical Distribution Characteristics and Drug-resistance of AmpC-producing Enterobacter cloacae in ICU
- VernacularTitle:重症监护病房产AmpC酶阴沟肠杆菌检测及耐药性分析
- Author:
Hongmei CHEN
;
Qinfang TANG
;
Hui ZHU
;
Huixiang JU
;
Mingzhong SUN
- Publication Type:Journal Article
- Keywords:
ICU;
Enterobacter cloacae;
AmpC ?-lactamase;
Drug-resistance
- From:
Chinese Journal of Nosocomiology
2009;0(18):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE To explore the clinical distribution characteristics and the drug-resistance of AmpC-producing Enterobacter cloacae in ICU. METHODS Seventy-eight strains of E. cloacae were isolated in ICU from Jan 2005 to Jan 2006 and antimicrocal sensitivities were determined by K-B method. RESULTS Among 78 E. cloacal strains derived from the lower respiratory tract and wound secretion,32 (41.0%) were AmpC producing and were sensitive to imipenem (96.9%) and merapenem (93.8%). CONCLUSIONS AmpC-producing E. cloacae is one of the main pathgens of nosocomial infection in ICU,imipenem and merapenem are the first choice to treat the infection.
