Prevalence of Extended-spectrum Beta-lactamases and Metallo-beta-lactamses among Chryseobacterium indologenes and Ch.gleum
- VernacularTitle:产吲哚金黄杆菌和黏金黄杆菌产?-内酰酶的研究
- Author:
Jiahe SHENG
;
Weiqiang XIAO
;
Qingxia XU
- Publication Type:Journal Article
- Keywords:
Chryseobacterium indologenes;
Chryseobacterium gleum;
Metallo-?-lactamases(MBLs)
- From:
Chinese Journal of Nosocomiology
2006;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE To study the incidence of ?-lactamases,mainly the extended-spectrum beta-lactamases(ESBLs) and metallo-beta-lactamases(MBLs) of Chryseobacterium indologenes and Ch.gleum.METHODS Agar dilution method was applied to detect minimal inhibitory concentrations(MIC) to 12 different antibiotics used frequently.Three-dimensional test was used to detect ESBLs and metallo-?-lactamases.The genes of ?-lactamases were amplified with 3 pairs of primers special for Ch.indologenes and Ch.gleum.RESULTS Among the 25 strains of Ch.indologenes and 10 strains of Ch.gleum,68%(17/25) isolates of Ch.indologenes and 90%(9/10)isolates of Ch.gleum were considered as MBLs positive strains,but no isolates were detected for the production of ESBLs.CONCLUSIONS MBLs are the important mechanism of multi-drug resistance for Ch.indologenes and Ch.gleum.
