Effects of polysaccharide from Sargassum fusiforme on blood-lipids and antioxidation ability in hyperlipemia rats
- VernacularTitle:羊栖菜多糖对高血脂模型大鼠血脂和抗氧化功能的影响
- Author:
Zunwen WANG
;
Yuqin HUA
;
Guoping LI
;
Yuefen LI
- Publication Type:Journal Article
- Keywords:
Sargassum fusiforme polysaccharide(SFPS);
hyperlipemia;
antioxidation
- From:
Chinese Journal of Marine Drugs
2000;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effects of polysaccharide from Sargassum fusiforme on blood-lipid and antioxidation ability in hyperlipemia rats.Methods The hyperlipemia rats as the experimental animal were established by feeding with fat-rich forage,meanwhile the rats were ig SFPS at doses of 0.4、0.8、1.6g?kg-1for 4wk.The levels of blood-lipid and the indices of antioxidation ability which include the total cholesterol(TC),triglyceride(TG),low-density lipoprotein cholesterol(LDL-C),high-density lipoprotein cholesterol(HDL-C),lipid peroxidation(LPO),malonaldehyde(MDA),superoxide dismutase(SOD) and glutathion peroxidase(GSH-Px) were determined.Results and Conclusion SFPS could significantly reduce the contents of TC,TG,LDL-C,LPO and MDA.In the mean time,SFPS increased the content of HDL-C and enhanced the activities of SOD and GSH-Px.
