Relationship between the expressions mP53 and microvessel density in urothelial carcinoma of the bladder and its clinical pathological significance
- VernacularTitle:膀胱尿路上皮癌突变型P53表达和微血管密度测定的意义
- Author:
Ye XU
;
Bingfeng GONG
;
Wei FAN
;
Yinxia LIU
- Publication Type:Journal Article
- Keywords:
Bladder urothelial carcinoma;
Immunohistochemistry;
mP53;
Microvessel density
- From:
Journal of Medical Postgraduates
2003;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the relationship between the expression mP53 and microvessel density urothelial carcinoma of the bladder and its clinical pathological significance. Methods: Immunohistochemistry(Envision method) was used to detect the expression of mP53 and FⅧ-RAg in 50 tissue specimens of primary BUC and 10 tissue specimens of normal mucosa of bladder .The results were analyzed with the clinic and pathological characters of BUC. Results: The expression of mP53 and MVD had significant differences between the tissues of normal mucosa of the bladder and the tissues of the BUC; but not related to the tumor size. mP53 and MVD value had correlation to different stages (according to UICC-TNM ), different grades (according to WHO), and recurrence(P
