Effects of Sleep Deprivation on Serum Cytokine Levels of Rats
- VernacularTitle:睡眠剥夺对大鼠血清细胞因子的影响
- Author:
Xingqu WU
;
Laiqi YANG
;
Xiaofen WANG
- Publication Type:Journal Article
- Keywords:
sleep deprivation immune cytokine rats
- From:
Chinese Mental Health Journal
1988;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To investigate the effects of paradoxical sleep deprivation (SD) on serum cytokine levels of Sprague-Dawley rats Method:Paradoxical sleep deprivation was induced in male rats by housing them on small platforms over water Controls were housed either in normal cages (CC) or in tanks with large platforms (TC) After SD for different lengths of time, serum levels of IL-2, 6, 8, TNF-? and cortisol of all groups were measured by double antibodies radio-immune assay Results: Serum level of TNF-? and cortisol of SD24h group were higher than that of CC (P
