Determination of oxymatrine in Compound Kushen Colon-specific Capsula by capillary electrophoresis
- VernacularTitle:高效毛细管电泳法测定复方苦参结肠溶胶囊中氧化苦参碱
- Author:
Zhanqi TONG
;
Jianyi GAO
;
Bingyue CHEN
- Publication Type:Journal Article
- Keywords:
Compound Kushen Colon-specific Capsula;
oxymatrine;
high performance capillary electrophoresis(HPCE)
- From:
Chinese Traditional and Herbal Drugs
1994;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To establish an HPCE method for the determination of oxymatrine in Compound Kushen Colon-specific Capsula.Methods Amphetamine sulfate was used as the internal standard.The separation was obtained with silica capillary column(50 cm ? 50 ?m,effective length 45 cm),30 mmol/L phosphate buffer(pH 5.8)at a constant voltage of 20 kV,and temperature at(25?1)℃,the detective wavelength 214 nm.Results The linear determination range was 30—240 ?g/mL and the average recovery and RSD were 99.54% and 1.85%,respectively.Conclusion The method is simple and accurate,and can be used for quality control of Compoud Kusheng Colon-specific Capsula.
