Study on Quality Standard for Shengxinfa Capsule
10.3969/j.issn.1005-5304.2013.07.022
- VernacularTitle:生新发胶囊质量标准研究
- Author:
Weifeng FAN
;
Shiyong WANG
;
Danxuan HE
;
Zhiwen YE
;
Qin LI
- Publication Type:Journal Article
- Keywords:
Shengxinfa Capsule;
quality standard;
TLC;
HPLC
- From:
Chinese Journal of Information on Traditional Chinese Medicine
2013;(7):59-60,61
- CountryChina
- Language:Chinese
-
Abstract:
Objective To establish the quality standard for Shengxinfa Capsule. Methods TLC was used to identify Praeparata, Psoraleae Fructus and Gastrodiae Rhizoma in Shengxinfa Capsule, and 2,3,5,4’-the four-stilbene-2-O-β-D-glucoside was identified by HPLC. The column of Agilent TC-C18 (4.6 mm×250 mm, 5 μm) was used. The mobile phase was acetonitrile-water (15∶85). The flow was 1.0 mL/min and column temperature was 30 ℃. UV detecting wavelength was 320 nm. Results Praeparata, Psoraleae Fructus and Gastrodiae Rhizoma could be identified by TLC. The linear range of 2,3,5,4’-the four-stilbene-2-O-β-D-glucoside was in the range of 0.05-0.50 μg. The average recovery was 97.8% (RSD=0.39%). Conclusion The method is feasible and accurate. The quality of Shengxinfa Capsule can be controlled effectively with the established quality standard.
