Mechanism of Biological Effects of ELF Pulsed Electromagnetic Wave on Cells
	    		
		   		
	    	
    	
    	
   		
        
        	
        		- VernacularTitle:极低频脉冲电磁场细胞生物效应及机制的研究
 
        	
        	
        	
        		- Author:
	        		
		        		
		        		
			        		Yongjun ZHOU
			        		
			        		;
		        		
		        		
		        		
			        		Zhongqi NIU
			        		
			        		
		        		
		        		
		        		
		        		
		        		
			        		
			        		
		        		
	        		
        		 
        	
        	
        	
        		- Publication Type:Journal Article
 
        	
        	
        		- Keywords:
        			
	        			
	        				
	        				
			        		
				        		pulse electromagnetic waves;
			        		
			        		
			        		
				        		Ca~(2+);
			        		
			        		
			        		
				        		biological effects;
			        		
			        		
			        		
				        		crystalline liquid biomembrane;
			        		
			        		
			        		
				        		eletrohydrodynamic instability
			        		
			        		
	        			
        			
        		
 
        	
            
            
            	- From:Space Medicine & Medical Engineering
	            		
	            		 2006;0(02):-
	            	
            	
 
            
            
            	- CountryChina
 
            
            
            	- Language:Chinese
 
            
            
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		        	Abstract:
			       	
			       		
				        
				        	Objective To observe changes of cytosolic Ca2+ levels before and after irradiation by ELF pulsed electromagnetic waves and to study the mechanism of these changes.Methods Basing on the result from experiment,time-frequency analysis was applied to analyze the bio-effects of ELF pulsed electromagnetic field on cytosolic Ca2+ levels.Results The PHMx(t,?)isoline of cytosolic Ca2+ levels of the cells before(a)and after(b)irradiation by ELF pulsed electromagnetic field was given.Electrohydrodynamic instability and a crystalline liquid biomembrane were applied to explain the mechanism of biological effects on the cells.Conclusion The cytosolic Ca2+ concentration represents a well-defined pattern of spectrum in time-frequency domain,containing continuous and dispersive spectral components.The circs which was considered to induce bio-effects in time-frequency domain presented two unique properties:the continuous spectrum of cellular Ca2+ fluctuations in time-frequency domain was narrowed by the high-energy spectrum component restrained,and the distribution and the frequencies of the dispersive spectra were changed.Furthermore,the pulse frequencies and intensities producing the bio-effects are discrete and distant.