Study on the Preparation of Garlic Oil ?-CD Sustained-release Tablet
- VernacularTitle:大蒜油?-环糊精包合物缓释片制剂工艺研究
- Author:
Yonghui SUN
;
Guiji WANG
;
Jianming WANG
- Publication Type:Journal Article
- Keywords:
Garlic oil ?-CD sustained-release tablet;
orthogonal design;
preparation technology
- From:
Chinese Journal of Information on Traditional Chinese Medicine
2006;0(11):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To optimize the formulation of the Garlic oil ?-CD sustained-release tablet. Methods The preparation formulation of the sustained-release tablet was optimized by orthogonal design which took the released rate as the index. Result The optimized formulation contained 9% HPMC, 15% lactose, 10% PVP, 10% microcrystalline cellulose. The ingredient of Garlic oil sustained-release tablet by this formulation was released slowly in 8 h. Conclusion The optimized formulation is rational and stable, the tablet could be released slowly.
