Heat-clearing and Toxicity-removing Therapy for the Treatment of Acute Coronary Syndrome: An Observation of 55 Cases
- VernacularTitle:清热解毒法治疗急性冠脉综合征55例
- Author:
Yanshou HUANG
;
Honghui MO
;
Yongdun HONG
;
Hui WU
- Publication Type:Journal Article
- Keywords:
CORONARY DISEASE/TCM-WM therapy;
SANHUANG XIEXIN DECOCTION/therapeutic use;
CLEARING HEAT AND REMOVING TOXICITY;
C-REACTIVE PROTEIN/blood;
TUMOR NECROSIS FACTOR/blood;
INTERLEUKIN 2/blood
- From:
Journal of Guangzhou University of Traditional Chinese Medicine
2001;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
[Objective] To observe the preventive effect and mechanism of heat-clearing and toxicity-removing therapy for the treatment of acute coronary syndrome (ACS), and to explore the relationship of ACS with inflammation. [Methods] Fifty five ACS patients were randomized into 2 groups:41 patients in group A were treated with Sanhuang Tablets (mainly composed of Radix et Rhizoma Rhei, Radix Scutellariae and Rhizoma Coptidis) p.o., 4 tablets one time, twice a day, and a routine treatment for anticoagulation, anti-platelet aggregation and anti-myocardial ischemia; 14 patients in group B were given routine treatment for anticoagulation, anti-platelet aggregation and anti-myocardial ischemia. The treatment course lasted 2 weeks. After treatment, improvement in symptoms such as chest pain, chest distension, short breath, palpitation, fever, spontaneous sweating, insomnia, lassitude, aversion to cold and cold limbs was compared between group A and group B by scoring method. Meanwhile, inflammatory indicators in the two groups were also observed before and after treatment. [Results] The decrease in symptom scores, as well as the decrease in blood C-reactive protein (CRP) , tumor necrosis factor a (TNF-?) and interleukin 6 (IL-6) , was obvious in group A than that in group B (P
