Effects of infrasound on rat myocardial cell and its underlying mechanism
- VernacularTitle:8Hz/130dB次声对大鼠心肌细胞的损伤作用研究
- Author:
Zhaohui PEI
;
Jingzao CHEN
;
Miaozhang ZHU
;
Ling LI
;
Zhiqiang ZHUANG
- Publication Type:Journal Article
- Keywords:
Infrasound;
Cardiac muscle damage;
Rats
- From:
Chinese Journal of Physical Medicine and Rehabilitation
2003;0(12):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the effects of infrasound on rat myocardial cells and to study its underlying mechanism. Methods One hundred Sprague-Dawley rats were divided into a normal control group and a infrasound exposure group, composed of various subgroups subject to exposure to infrasound for 2 hours daily for 1 d,7 d,14 d,21 d,and 28 d, respectively. The ultra-microstructure and apoptosis of the rat myocardial cells were observed, and SOD and MDA were measured. Results After exposure to infrasound, significant ultra-microstructural impairment and increased apoptosis of the myocardial cells were observed in the infrasound exposure group as compared to those of the normal control group,(P
