Research on drug content and encapsulated efficency of Ophiopogon saponin enteric microphase
- VernacularTitle:麦冬皂苷肠溶微球的载药量和包封率研究
- Author:
Yi FENG
;
Lan SHEN
;
Dengsheng XU
;
Xiaoru WU
- Publication Type:Journal Article
- Keywords:
ophiopogon saponin;
enteric microsphere;
drug content;
encapsulated efficency
- From:
Chinese Traditional Patent Medicine
1992;0(08):-
- CountryChina
- Language:Chinese
-
Abstract:
AIM: To explore the effect of drug content and encapsulated efficency of microsphere ophiopogon saponin preparation, providing more precise computational method. METHODS: Ophiopogon saponin enteric microsphere was prepared by spray drying technique, and the sum of saponin was determined by colorimetric analysis to evaluate the drug content and encapsulated efficency. RESULTS: The encapsulated efficency (%) was 94.75? 2.68. The drug content (mg/g) was 54.81? 2.12. CONCLUSION: The drug content the encapsulated efficency can affect the clinical dosage and the encapsulated efficency stands for the preparation process and the quality. So we should detect both drug content and the encapsulated efficency to evaluate preparation quality evaluation.
