Research progress of peptide drugs for treatment of autoimmune diseases
10.3969/j.issn.1001-1978.2014.05.031
- VernacularTitle:治疗自身免疫性疾病多肽药物的研究进展
- Author:
Xuefeng WANG
;
Liyang DONG
;
Jun WANG
;
Hongchang NI
;
Chuan SU
- Publication Type:Journal Article
- Keywords:
autoimmune diseases;
peptide;
drugs;
therapy;
progress;
specific epitopes
- From:
Chinese Pharmacological Bulletin
2014;(5):732-734,735
- CountryChina
- Language:Chinese
-
Abstract:
Recent studies have found that peptide therapies tar-geting specific epitopes can avoid nonspecific immune suppres-sion induced by traditional medicines for the treatment of autoim-mune diseases, and have shown great therapeutic effect in ani-mal models of autoimmune diseases and clinical trials. The pa-per summaries the research progress and trends of peptide drugs for the treatment of autoimmune diseases from candidate peptide sources and their suppression mechanisms, which can provide a theoretical basis for the in-depth understanding of immune toler-ance and allow for discovery of new treatment for autoimmune diseases.
