Outcome of double-valve replacement for rheumatic heart disease in patients under 20
	    		
		   		
	    	
    	
    	
   		
        
        	
        		- VernacularTitle:20岁以下风湿性心脏病双瓣膜替换术疗效观察
 
        	
        	
        	
        		- Author:
	        		
		        		
		        		
			        		Yuequan JIANG
			        		
			        		
		        		
		        		
		        		
		        		
		        		
			        		
			        		
		        		
	        		
        		 
        	
        	
        	
        		- Publication Type:Journal Article
 
        	
        	
        		- Keywords:
        			
	        			
	        				
	        				
			        		
				        		Heart valve diseases;
			        		
			        		
			        		
				        		Double valve implantation
			        		
			        		
	        			
        			
        		
 
        	
            
            
            	- From:
	            		
	            			Journal of Chongqing Medical University
	            		
	            		 1987;0(01):-
	            	
            	
 
            
            
            	- CountryChina
 
            
            
            	- Language:Chinese
 
            
            
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		        	Abstract:
			       	
			       		
				        
				        	Objective:To analyse the intermediate-term morbidity and mortality of rheumatic heart disease in patients under the age of 20 years treated with mitral-aortic valve replacement.Methods:A retrospective study was conducted on 55 consecutive patients who underwent mechanical double-valve replacement(DVR) from January,1989 to January,2002.Among the 55 cases,33 were male and 22 female with a mean age of 16.3 years (range 10~20 years).The mean follow up was 4.6 years (maximum 11 years).Results:The operative mortality was 7.3%(4 patients).There was of 2% mortality reported(1 case) in 10 years.At a mean follow-up period of 4.6 years,there was an improvement in functional class from 2.6 to 1.1.There were no increasing incidence of thrombo-embolic and anticoagulant related hemorrhagic events in this study group.Conclusion:The functional results of survivors of DVR performed in the first 2 decades of life are satisfactory.Use of combined warfarin and antiplatelet therapy is appropriate in this age group following DVR (with mechanical valves) for RHD in the aortic-mitral position.