Study of inhibition function of Qingjiening on cytokine in SRBC-immunized mice
- VernacularTitle:清解宁对SRBC免疫小鼠细胞因子抑制作用的研究
- Author:
Junguo REN
;
Quanying QIU
;
Yu HAO
;
Jinli LOU
;
Xiujuan HE
- Publication Type:Journal Article
- Keywords:
Qingjiening;
cytokine;
IL-1;
IFN-?;
IL-2;
mouse
- From:
Chinese Traditional Patent Medicine
1992;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
AIM: To investigate the effect of Qingjiening(QJN) on cytokines in sheep red blood cell(SRBC)-immunized mice. METHODS: After immunization of mice with SRBC, the effect of QJN o n IL-1、IFN-?、IL-2 in mice was observed, the IFN-? level was measured by macrophage NO - 2-release assay, the IL-1 level was measured by thymocyte a ssay, the IL-2 level was measured by mitogen activated lymphocytoblast assay. RESULTS: QJN can significantly inhibit mice to secrete IL-1、IFN- ? and IL-2. CONCLUSION: The immunosuppressive activity of QJN may be associate d with inhibition of immunocyte to secret IL-1、IFN-? and IL-2.
