An Experimental Study on the Mechanism of Fever in Damp - Heat Syndrome
- VernacularTitle:湿热证缠绵难愈的病理机制探讨
- Author:
Zhibing WU
;
Shengquan PENG
;
Peizheng UN
;
Jiaxi ZHONG
;
Tong SHU
- Publication Type:Journal Article
- Keywords:
SEASONAL PREVALENT DISEASES/TCM pathogenesis;
DAMP- HEAT SYNDROME/TCM pathogenesis;
HYPERLIPIDEMIA;
ENDOTOXINS;
TUMOR NECROSIS FACTOR/blood;
INTERLEUKIN-1/blood;
RABBITS;
DISEASE MODELS, ANIMAL
- From:
Journal of Guangzhou University of Traditional Chinese Medicine
2001;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
[Objective] To explore the mechanism of fever in damp- heat syndrome. [Methods] Hyperlipemia rabbit models were established by feeding fatty - sweet diet. After the injection of endotoxin, the secretion of tumor necrosis factor and interleukin 1 was observed in rabbit model (Group A) and compared with normal rabbits (Group B) . [ Results] The peak of tumor necrosis factor and interleukin 1 secretion was decreased and the decline was slow in Group A. [ Conclusion ] The damp - heat syndrome in seasonal febrile disease is not merely a simple addition of damp and heat, but a result of retention and interaction of the two factors.
