Influence of Red Sage and Propranolol on Portal Hypertension Rats' Pressure,Liver Fibrosis and Gastric-intestinal Hormone
- VernacularTitle:丹参、心得安对门静脉高压症大鼠门静脉压力、肝纤维化指标及胃肠激素的影响
- Author:
Xiaoqi XU
;
Min LI
;
Erli GU
- Publication Type:Journal Article
- Keywords:
liver fibrosis;
portal hypertension;
Red Sage;
propranolol;
gastro-intestinal hormone;
liver function
- From:
Journal of Zhejiang Chinese Medical University
2006;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
[Objective] To observe the influence of Red Sage and Propranolol on portal hypertension rats' pressure,liver fibrosis and gastric-intestinal hormone.[Method] At 4w after making models,rats take the said medicines,then measure their portal pressure with biological signal Medlab-Ug4Cs collection and treatment system;after decapitation,measure the indexes with radio-immune method.[Result] In model group(1),the portal pressure is much more increased than normal one(2),that in Red Sage treatment(3) and Propranolol(4) groups is much lowered,so are gastrin and glucagon;compared to group 1,the gastrin,motilin and glucagon in group 3 are much decreased,so are compared to group 4.[Conclusion] Red Sage can effectively reduce portal pressure,liver fibrosis index and regulate gastro-intestinal hormone,with cure effect better than propranolol.
