Relationship between plasma cortistatin and coronary heart disease
- VernacularTitle:血浆皮质醇激素抑制素水平与冠心病的关系
- Author:
Qingping TIAN
;
Xueru FENG
;
Yongzheng PANG
;
Chaoshu TANG
;
Meilin LIU
- Publication Type:Journal Article
- Keywords:
Neuropeptides;
Coronary disease;
Angioplasty,transluminal,percutaneous coronary;
Cortistatin
- From:
Journal of Peking University(Health Sciences)
2003;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To analyze the relationship between plasma level of cortistatin(CST) and coronary heart disease(CHD) and the factors that influence the level of CST.Methods: Plasma levels of CST were measured using ELISA method.The clinical data and the levels of CST of 40 healthy subjects and 39 CHD patients before and 1 d after percutaneous coronary intervention(PCI) were compared.And the factors that influenced the CST level were analyzed.Results: The CST levels of CHD group before or 1 d after PCI were significantly higher than those of the control group(1.97?1.12 and 2.01?0.77 vs 1.21?0.27,P0.05);There was no correlation between CST levels and fasting blood glucose(FBG),high sensitivity C-reactive protein(hsCRP),left ventricular ejection fraction(LVEF),severity of lesions of coronary arteries or history of hypertension;The levels of triglyceride(TG) and total cholesterol(TCHOL) negatively correlated with CST levels(?=-2.594,P
