Expressions of Protease Activated Receptors on Human monocyte.
- VernacularTitle:蛋白酶激活受体在人单核细胞上的表达
- Author:
Zhiqiang ZOU
;
Tao LI
;
Zhenqi CHEN
;
Wen ZHUANG
;
Tingjun LI
;
Jinzhong ZHANG
;
Xianghui YANG
- Publication Type:Journal Article
- Keywords:
Protease activated receptors;
Monocyte;
RT-PCR;
Flow cytometry
- From:
Journal of Medical Research
2006;0(10):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the expression of protease activated receptors (PARs) on human monocytes. Methods Flow cytometry and RT - PCR was used to detect the expressions of PARs on human monocytes that purified by MACS. Results FACS analysis showed that monocytes expressed PAR - 1 , PAR - 3 , PAR - 4, but not PAR - 2.RT - PCR revealed that monocytes expressed PAR - 1 and PAR -3, but not PAR -2 and PAR -4 mRNA. Conclusion PARs is expressed on human monocyte cells,which may facilitate further investigation of the potential functions of PARs on monocytes.
