Expression and Meaning of NOS and BDNF in the Lateral Zone of Rats’ Hypothalamus with Diabetes
- VernacularTitle:NOS和BDNF在糖尿病大鼠下丘脑外侧区的表达及其意义
- Author:
Hangfang LOU
;
Yueming ZHANG
- Publication Type:Journal Article
- Keywords:
diabetes;
nitric oxide synthase;
nerve nutrition gene;
brain neuron;
hypothalamus
- From:
Journal of Zhejiang Chinese Medical University
2006;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
[Objective] To discuss the expression and meaning of NOS and BDNF in the lateral zone of rats’ hypothalamus with diabetes. [Method] Inject STZ 50mg/kg into the abdomen for rats model of diabetes, after 1 month, observe the positive neuron expression of LH NOS in rats’ hypothalamus with diabetes with NADPH-d enzyme histo-chemical method, to the positive neuron expression of LH BDNF with NADPH-d immunohisto-chemical method. [Result] The expression of NOS and BDNF is both lowered compared with normal group, P
