Effect of astragalus polysaccharides and soy isoflavones on glucose metabolism in diabetic rats
- VernacularTitle:黄芪多糖和大豆异黄酮对糖尿病大鼠糖代谢的影响
- Author:
Weiping LIAO
;
Yuangang SHI
- Publication Type:Journal Article
- Keywords:
astragalus polysaccharides;
soy isoflavones;
diabetes mellitus
- From:Journal of Third Military Medical University
1988;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the effect of astragalus polysaccharides (APS) and soy isoflavones (SI) on glucose metabolism in diabetic rats. Methods Healthy 60 rats were equally and randomly divided into 5 groups, normal forage group (NF), high blood sugar model group(HBS), APS high dose group intervention group (APS-H), APS low dose group (APS-L), and SI intervention group (SI). Diabetic model was inflicted by intraperitoneal injection of streptozotocin (STZ). Ordinary feed and APS high dose,low dose APS and SI interfere were respectively given for 8 weeks. Blood glucose,glycated hemoglobin,glucose and lipid levels were determined in every group. Results After APS high dose,low dose and SI were given to feed diabetic rats for 8 weeks, their blood glucose, glycated hemoglobin, glucose, TC, TG, LDL, VLDL and high blood glucose was significantly lower than the HBS group (P
