Therapeutic effects of polysaccharide from B.Jiangsiensis against hepatitis B virus in vivo and vitro
- VernacularTitle:天螺霜抗乙型肝炎病毒作用的研究
- Author:
Chao ZHANG
;
Min LUO
;
Qingzhi LING
;
Tianyi CHEN
- Publication Type:Journal Article
- Keywords:
Polysaccharide from B.Jiangsiensis/pharmacology;
Hepatitis B virus;
Polymerase chain reaction;
Disease models,animal;
Ducks
- From:
Chinese Journal of Primary Medicine and Pharmacy
2006;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the therapeutic effect of tianluo decoction against hepatitis B virus(HBV) in vivo and vitro.Methods The inhibitive effect were observed in the duplication process of hepatitis B virus by fluorescence quantitative PCR(FQ-PCR) in vitro test and duck's hepatitis B animal model in vivo test.Results FQ-PCR in vitro test demonstrated that tianluo decoction had biological function to inhibit from duplication of hepatitis B virus,and there were significant difference in inhibit hepatitis B virus from duplicating in distilled water and tianluo decoction group(median:6.9?108/ml vs 2.6?104/ml,u=2.76,P
