Characteristics of inverse agonist action
- VernacularTitle:反向激动剂的药理效应特征
- Author:
Houli ZHANG
;
Zeyao TANG
;
Jingxian YANG
;
Yuan LIN
- Publication Type:Journal Article
- Keywords:
inverse agonist;
agonist;
antagonist
- From:
Chinese Pharmacological Bulletin
2003;0(11):-
- CountryChina
- Language:Chinese
-
Abstract:
Inverse agonist is a new type of classification.Different form antagonist that blocks the effect of agonist,inverse agonist produces opposite effect to that of agonist.The characteristics of inverse agonists acting on different receptors including H_2,H_3,? opioid,adrenergic ?, and 5-HT_((1B)) receptors are discussed in this paper.Recent investigation suggested that inverse agonist has potential clinical application.
