Dynamic changes of CD34~+ cell and T lymphocyte subset from different populations after G-CSF treatment
- VernacularTitle:G-CSF对不同人群CD34~+细胞及T细胞亚群影响的动态变化研究
- Author:
Cunbang WANG
;
Xinghua CHEN
;
Yingxian OU
;
Hai BAI
;
Yaming WEI
;
Jianfeng OU
;
Haixia MU
;
Xiaojin WANG
- Publication Type:Journal Article
- Keywords:
G-CSF;
bone marrow;
peripheral blood;
CD34 + cells;
T lymphocyte subset
- From:Journal of Third Military Medical University
2002;0(12):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the dynamic changes of CD34 + cells and T lymphocyte subsets and best time of harvesting peripheral blood stem cell when G-CSF was used for peripheral blood stem cell mobilization in donors and patients. Methods A total of 12 donors and 16 patients who received chemotherapy for 7 d were injected G-CSF of 300 ?g/d to mobilize peripheral blood stem cells for 5 d and flow cytometry were used to detect the changes of CD34 + cells and T lymphocyte subsets everyday for 5 d. Results ① Before G-CSF treatment, there were obvious differences in bone marrow CD34 + cells between patients and donors (P
