EFFECTS OF HYDROLYSED CASEIN ON ANTIOXIDATIVE ENZYMES IN MICE
- VernacularTitle:酪蛋白酶解物对小鼠抗氧化酶活性的影响
- Author:
Wenqin HU
;
Tian WANG
;
Yanmin ZHOU
;
Guijuan LIN
- Publication Type:Journal Article
- Keywords:
casein hydrolysates;
superoxide dismutase;
glutathione peroxidase;
malondialdehyde
- From:
Acta Nutrimenta Sinica
1956;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To study the effects of hydrolysed casein in different doses on plasma and liver antioxidant capacities in mice. Methods: Fifty mice were divided into 5 groups: control group, vitamin E group (VE), low dose of hydrolysed casein group (CH1), medium dose of hydrolysed casein group(CH2)and high dose of hydrolysed casein group(CH3). The mice were supplemented with 0.25ml normal saline,7.2 mg/ml Vitamin E,4,12 and 20 mg/ml hydrolysed casein respectively by gavage one time a day. The mice were euthanatized after ten days. The activities of SOD, GSH-PX and the level of MDA were determined. Results: Hydrolysed casein in different dosese vidently increased the activities of SOD and GSH-Px in serum, and reduced the level of MDA in serum and liver of mice; group CH3 significantly increased the activities of GSH-Px in liver. Conclusion: Different doses of hydrolysed casein could raise plasma and liver antioxidant capacities in mice, especially the high dose of hydrolysed casein.
