Clinical analysis of 61 cases of drug eruptions complicated with drug-induced liver dysfunction
- VernacularTitle:61例药疹伴药物性肝损害住院病例临床分析
- Author:
Qiuhe SONG
;
Lu WANG
;
Qingyi YE
;
Baiyu ZHONG
- Publication Type:Journal Article
- Keywords:
drug eruption;
drug-induced liver dysfunction;
allergic reaction
- From:Journal of Third Military Medical University
2003;0(23):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate whether the sort of drugs causing drug eruptions complicated with drug-induced liver dysfunction are the same as those causing drug eruptions. Methods Sixty-one cases of drug eruption complicated with drug-induced liver dysfunction in 261 cases confirmed as drug eruptions from January 1998 to March 2003 were analyzed retrospectively. Results The major hepatotoxic drugs in these cases were antivirus drugs (60%, 9/15), antituberculosis drugs (66.67%, 8/12), zyloric (55.56%, 5/9), and some traditional Chinese medicines (31.58%, 6/19). Conclusion The sort of drugs causing drug eruptions complicated with drug-induced liver dysfunction are the same as those causing drug eruptions, which should be taken into consideration in clinical medication.
