The prophylactic effects of statins on cardiovascular events in patients with normal level of plasma lipids
- VernacularTitle:他汀对血脂正常者的心血管事件预防作用
- Author:
Zechang XU
;
Baoxian PEI
- Publication Type:Journal Article
- Keywords:
statin;
coronary heart disease;
LDL-C;
lipid
- From:
Chinese Pharmacological Bulletin
2003;0(11):-
- CountryChina
- Language:Chinese
-
Abstract:
Primary and secondary prevention clinical trials have demonstrated that statins markedly reduced cardiovascular risks even in patients whose plasma level of low-density lipoprotein cholesterol is lower than that of drug-treatment goal in lipid management guidelines. The reasons are as follows: The "normal" level in guidelines is not the normal level biologically, it is merely an average value in a given human group; The composition of plasma lipids is very complex; Statins have effects other than lipid modifying. Statins should be prescribed in patients without hyperlipidemia but with risk factors or coronary heart disease.
