EXPRESSIONS OF CD3 ,CD20,CD68 IN EARLY SYPHILIS LESIONS
- VernacularTitle:早期梅毒皮损组织CD3、CD20和CD68的表达
- Author:
Xiaodong ZHANG
;
Chaowei TUO
;
Fangji SONG
- Publication Type:Journal Article
- Keywords:
syphilis, skin;
CD3;
CD20;
CD68;
immunity, cellular;
immunohistochemistry
- From:
Medical Journal of Chinese People's Liberation Army
2001;0(11):-
- CountryChina
- Language:Chinese
-
Abstract:
To probe course and mechanism of cellular immune respone in early syphilitic lesion, the expression levels of CD3, CD20, CD68 were determined by immunohistochemistry and a computer image analysis system. The results showed that the expressions of CD3, CD20, and CD 68 were positive in 43 cases of primary and secondary syphilis. The expression level of CD68 was higher thanthat of CD3, CD20, especially around blood vessels. The expression level of CD 20 was very low. This study indicates that T cells, B cells, and in particular macrophages play an important cellular immunologic regulating role in clearance of Treponema pallidum from the infected tissue, but the efficacy is not high enough.
