Surveillance of antimicrobial resistance in clinical isolates from intensive care units during 2012
10.3969/j.issn.1671-8348.2013.25.026
- VernacularTitle:2012年重症监护病房细菌耐药监测
- Author:
Li YAN
;
Siqiang NIU
;
He CAO
;
Ping YANG
;
Xiaobing ZHANG
;
Shifeng HUANG
;
Xiaoheng ZHANG
;
Shan SUN
;
Xiuli HE
- Publication Type:Journal Article
- Keywords:
bacterium;
antimicrobial;
drug resistance;
ICU
- From:
Chongqing Medicine
2013;(25):3022-3023,3025
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the antimicrobial resistance of main clinical isolates from ICU during 2012 .Methods Auto-matic microbiology analysis system and the disk diffusion method were performed to determine the antimicrobial susceptibility .All the data were analyzed by WHONET5 .6 software according to the breakpoints of The American Association of Clinical Laboratory Standardization Institute (CLSI) 2012 .Results A total of non-repeated 1 374 clinical isolates were collected in ICU during 2012 , including 1 089 strains (79 .3% ) of Gram-negative bacilli and 285 strains (20 .7% )of Gram-positive cocci ;The top five pathogens were Acinetobacter baumannii ,Pseudomonas aeruginosa ,Escherichia coli ,Klebsiella pneumoniae and Staphylococcus aureus ;Some Enterobacteriaceae strains were resistant to imipenem or ertapenem .2 strains of Enterococcus faecium were found resistant to van-comycin .Conclusion Non-fermenting bacteria ,Enterobacteriaceae and Staphylococci remain the predominant pathogens isolated from the patients in ICU ,their drug resistance is serious ,it is important to use antibacterial agents rationally and strengthen the sur-veillance of bacterial drug resistance .
