Preparation of Protein C Deficient Plasma
- VernacularTitle:缺蛋白C血浆的研制
- Author:
Xiaopu XIAO
- Publication Type:Journal Article
- Keywords:
PC;
PCDP;
McAb;
Affinity chromatographic column
- From:
Chinese Journal of Blood Transfusion
1988;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
A specific monoclonal antibody(McAb),which could identfy different conformations of protein C(PC) in the presence or absence of Ca24+ .was selected and coupled with Sepharose-4B gel to form an affinity chromatographic column. When fresh plasma passed through this column.its PC would he adsorbed exclusively,and the obtained effuent was PC-deficient plasma (PCDP). The residual PC in the PCDP gained was
