The effect of total glycoside of Rhubarb, Emodin and Sennosides on transmural potential of mouse intestine in vitro
- VernacularTitle:大黄总甙、大黄素和番泻甙对小鼠离体肠管葡萄糖转运电位的影响
- Author:
Zhiqing GUI
;
Shiduo GUO
;
Shuhua LI
- Publication Type:Journal Article
- Keywords:
Total glycoside of Rhubarb;
Emodin;
Sennosides;
Glucose;
Transmural potential difference
- From:
Chinese Pharmacological Bulletin
1986;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
The electrical potential difference (PD) was measured across the wall of reverted intestinal sacs. The effect of the effective component of Rhubarb on transmural potential related to Na+ and glucose transport were investigated. It was found that total glucoside of Rhubarb, Emodin and Sen-nosides decreased the PD. The experimental resuilts provide new scientific basis for explaining the mechanism of Rhubarb's purgative action.
