EARLY DIAGNOSIS AND TREATMENT OF ACUTE TRANSFORMATION OF CHRONIC GRANULOCYTIC LEUKEMIA
- VernacularTitle:慢性粒细胞性白血病急性变早期诊断及治疗的探讨
- Author:
Haichuan LIU
;
Shanqian YAO
;
Cifen LI
- Publication Type:Journal Article
- From:
Medical Journal of Chinese People's Liberation Army
1982;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
61 cases of chronic granulocytic leukemia were reviewed in this paper. Based on the results, the following features are suggested as the diagnostic criteria for early acute transformation: (1) fever of unknown cause, (2) bone and joint pain, (3) a fall in hemoglobin, marked increase or decrease of the number of WBC's and platelets, (4) myeloblasts and promyelocytes exceed 5% in peripheral blood and 10% in bone marrow, and (5) poor or no response to previously effective drug therapy, It is also suggested that a rational therapeutic management in the chronic phase may help to prevent or delay acute transformation.
