Significance of evaluating Th1/Th2 type cytokines in plasma of ovarian cancer patients
- VernacularTitle:Th1/Th2类细胞因子检测在卵巢癌中的意义
- Author:
Ligong SUN
;
Lixin SUN
;
Lijuan YAN
;
Ruixia ZHAO
;
Shuli SHAO
;
Shaoyun ZHANG
- Publication Type:Journal Article
- Keywords:
Th1/Th2 type cytokines;
Ovarian cancer
- From:
Cancer Research and Clinic
2006;0(12):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the variance and significance of Th1/Th2 type cytokines in plasma of ovarian cancer patients. Methods The levels of IL-2, IFN-?, TNF-?, IL-4, IL-6, IL-10 in 34 plasma samples of ovarian cancer patients and 14 normal women were detected by cytometric bead array. Results The levels of IL-2, IFN-?, TNF-? in ovarian cancer patients were obviously lower than those in normal womens but the levels of IL-4, IL-6, IL-10 were obviously higher. Furthermore, the variance changed along with clinic stage. Conclusion It is suggested that the imbalance of Th1/Th2 type cytokines in ovarian cancer patients may provide clinical index for the evaluation of progression and prognosis.
